NEW YORK TIMES, Sept. 3, 1858  The front page is almost entirely taken up with much detail on the burning of the Quarantine Hospital, the city's first line of defense against migrant-borne infectious diseases. First column heads included: "THE STATEN ISLAND ARSON "Full Details of the Burning of the Quarantine Buildings" "Boasts of the Incendiaries" "The Unsheltered Sick" and more.
Page 4 includes: "Later From Utah--Movements of Troops--The Utah Election--Everything Quiet"  as well as a brief item on: "The Slaver Echo", noting: "...that the Africans be retained by the U.S. Marshal & that they are not subject to the laws of South Carolina."
Eight pages, nice condition.

Background: This specific issue of The New York Times captures a critical, multi-faceted turning point in mid-19th-century American history, illustrating the intense convergence of nativism, federal-state friction, and the looming crisis over slavery. The front-page destruction of the Staten Island Quarantine Hospital—spurred by local fear of migrant-borne disease—stands as one of the most violent acts of nativist vigilante arson in U.S. history, fundamentally reshaping public health policy and accelerating the institutional medical segregation of immigrants. Meanwhile, the brief updates from Utah and South Carolina underscore a federal government stretched thin by territorial defiance; the fragile peace following the Utah War marked a uneasy containment of the Mormon rebellion, while the seizure of the slaver Echo intensified the volatile sectional crisis. By asserting federal custody over the liberated Africans against South Carolina's state laws, the Echo incident previewed the explosive legal and moral battles over federal authority and human bondage that would ultimately ignite the American Civil War just three years later.