THE WEEKLY REGISTER, Baltimore, Sept. 8, 1821 

* Death of Napoleon Bonaparte 
* Slavery & William Wilberforce

 Beginning on page 2 is a report of the death of: "Napoleon Bonaparte" which is prefaced with: "The following particulars are interesting, and seem necessary to assist in affording an account of the exit of the man who, for so many years, had occupied the attention of all the civilized world..." with a subhead: "Official Account of His Decease" and further on is another subhead: "Of the Causes of His Death". This report takes nearly 2 pages.
Among other reports in this issue are: "Debates on the Slave Trade" from the British House of Commons, including a lengthy address by Mr. Wilberforce (of "Amazing Grace" fame), this report taking over 4 pages. Also: "Effects of Slavery" and a document signed by: Simon Bolivar.
Sixteen pages 6 1/4 by 9 3/4 inches, nice condition.

Background: The September 8, 1821 issue of The Weekly Register (Niles' Weekly Register) stands as a monumental snapshot of global political transformation, capturing three defining movements of the early nineteenth century within a single sixteen-page edition. At its core, the issue delivers the definitive news of Napoleon Bonaparte's death and decease on St. Helena—alongside the official medical account detailing the causes of his death—marking the permanent collapse of the Napoleonic Era and the end of a figure who had dominated European geopolitics for decades. Concurrently, the publication highlights the pivotal parliamentary debates on the slave trade, featuring a lengthy address by anti-slavery crusader Mr. Wilberforce alongside essays on the broader effects of slavery, illustrating the intense international momentum toward abolitionism during this era. Framing this shift toward liberty, the included document signed by Simon Bolivar underscores the unraveling of the Spanish Empire and the birth of independent South American republics, making this issue an extraordinary historical record that connects the fall of European empire, the crusade against human bondage, and the rise of Latin American independence.

As noted in Wikipedia, this title: "...(was) one of the most widely-circulated magazines in the United States...Devoted primarily to politics...considered an important source for the history of the period."