THE NEW YORK TIMES, Oct. 25, 1872 

* Equine influenza - horse epidemic
* 1972 North American outbreak
* Ulysses S. Grant election notice
* Civil War general for president

The top of the back page has a one column heading: "THE HORSE PLAGUE" with subheads. (see images) Text takes up over 2 columns.
A top of page 4 notice endorses the Grant-Wilson ticket. (see)
Complete with 8 pages, nice condition.