SAN DIEGO DAILY UNION, California, Nov. 11, 1871  Very early from San Diego--a volume 2 issue--when the population was just 2300, with a nice engraving of the harbor in the masthead. 
The front page has: "The Situation In Arizona" with subheads: "The New Indian Policy--Exertions of Gov. McCormick" "Vindication of the People of Arizona" "Protest Against Colyer's Acts".
The Colyer referred to is Vincent Colyer, an American artist noted for his images of the American West. He was a humanitarian who worked with the U.S. government to try to help freedmen and Native Americans.
Four pages, 12 by 18 inches, printed on high-quality newsprint, very nice condition.