DAILY NATIONAL INTELLIGENCER, Washington, D.C., Aug. 19, 1852  The front page has a small notice for: "Uncle Tom's Cabin As It Is, being narratives, scenes, and Incidents of the real 'Life Among the Lowly', by W. L. G. Smith...". 
Uncle Tom's Cabin is an anti-slavery novel by American author Harriet Beecher Stowe. It had a profound effect on attitudes toward African Americans and slavery in the U.S., and is said to have helped lay the groundwork for the Civil War. 
In the U. S., Uncle Tom's Cabin was the best-selling novel and the second best-selling book of the 19th century, following the Bible.
Page 3 has an ad: "Wanted, a Colored Woman (a slave preferred), to cook, wash, and iron for a small family...". 
Four pages, nice condition.