DAILY NATIONAL INTELLIGENCER, Washington, D.C., Jan. 8, 1848  When it comes to "famous utterances" of the 19th century, this issue has one.
Most of page 2 is taken up with: "Speech of Mr. Calhoun, of South Carolina, In the Senate of the United States, January 4, 1848." This is a very notable speech by Calhoun, many website devoted to this.  
Calhoun, senator from South Carolina and future spokesman for southern secession, delivered this speech to Congress on January 4, 1848.  At the time, U.S. and Mexican diplomats were in the midst of negotiating a peace treaty to determine how much of Mexico would be incorporated into the U.S. Calhoun argued for limiting territorial expansion in order to restrict the number of non-white people who would become U.S. citizens. Other argued that all of Mexico should be annexed to the U.S.
Terrific to have this notable speech in a Washington, D.C. newspaper, from the city where it was given.
Four pages, nice condition.